When considering transition, not only is collaboration important, but under the right conditions it can lead to desired outcomes for youth with disabilities in transition from school to careers and adult life. In addition to the teachers and education professionals who have an obvious and direct role with youth with disabilities, others among the long list of potential collaborators in student/youth transition and student/youth employment are: vocational rehabilitation, youth service organizations, employment service agencies, government sponsored disability employment services, the workforce investment system, other community organizations and services, and employers. This Guide is designed to provide basic information to enable meaningful and outcome oriented collaboration among all of these potential partners.